HIV stands for human immunodeficiency virus. The virus can lead to acquired immunodeficiency syndrome, or AIDS, if not treated. Unlike some other viruses, the human body can’t get rid of HIV completely, even after treatment.
Right now, there is no cure for HIV. But with proper medical care, HIV can be effectively controlled. Treatment for HIV is called antiretroviral therapy or ART. If taken as prescribed, ART can dramatically prolong the lives of many people who have HIV and keep them healthy. Also, people with HIV who take HIV medicine as prescribed and keep an undetectable viral load will not transmit HIV through sex. Before the introduction of ART in the mid-1990s, people with HIV could progress to AIDS (the last stage of HIV infection) in a few years. Today, someone who gets an HIV diagnosis and starts treatment in the early stages of the disease can live nearly as long as someone who does not have HIV.
HIV attacks the body’s immune system , specifically the CD4 cells . These special cells help the immune system fight off infections. If HIV isn’t treated, it reduces the number of CD4 cells in the body. This damage to the immune system makes it harder and harder for the body to fight off infections and some other diseases.
If HIV infection isn’t treated, a person is more likely to get other infections or infection-related cancers. These opportunistic infections or cancers take advantage of a very weak immune system and make the person even sicker.
Opportunistic illnesses are infections and infection-related cancers that are more common or more severe in people with HIV because their immune systems are damaged. Examples include Kaposi's sarcoma, lymphoma, tuberculosis, and pneumonia.
Only certain body fluids —from a person with HIV can transmit HIV. The body fluids that can transmit HIV are blood, semen (cum), pre-seminal fluid (pre-cum), rectal fluids, vaginal fluids, and breast milk. For transmission to occur, these fluids must come in contact with a mucous membrane or damaged tissue or be directly injected into the bloodstream (from a needle or syringe) of a person without HIV. Mucous membranes are found inside the rectum , vagina, penis, and mouth.
You can get or transmit HIV only through specific activities. Most commonly, people get or transmit HIV through sexual behaviors and needle or syringe use. However, there are ways to greatly reduce your risk of getting or transmitting HIV from these activities, such as
Learn more about how HIV is and isn’t transmitted in the United States.
More Information
HIV is most often transmitted by
Less commonly, HIV may be transmitted by
In extremely rare cases, HIV may be spread by
HIV isn’t transmitted by
CDC's HIV Basics
About 1.2 million people in the United States have HIV. In 2018, nearly 38,000 people received an HIV diagnosis in the United States and dependent areas. Though the number of new HIV diagnoses has declined over the last few years, the number of people who have HIV has been increasing because people with HIV are now living longer.
In 2018, 81% of new diagnoses in the United States and dependent areas were among adult and adolescent men and 19% were among adult and adolescent women. Most new HIV diagnoses among women were from heterosexual contact (85%), and another 15% were from injection drug use. By age, 21% of new HIV diagnoses in 2018 were among young people aged 13 to 24, 36% were among people aged 25 to 34, 19% were among people aged 35 to 44, 14% were among people aged 45 to 54, and 10% were among people aged 55 and older.
When you live in a community where many people have HIV infection, the chances of having sex with someone who has HIV are higher. This interactive atlas allows you to see the rates of HIV infection (“prevalence ”) in different US communities. Within any community, the prevalence of HIV can vary among different populations.
HIV is transmitted when engaging in risky behaviors, like (1) having anal or vaginal sex without a condom or without taking medicine to prevent or treat HIV and (2) sharing needles, syringes or other injection equipment (for example, cookers). Certain cultural and societal factors can also play a part in HIV risk. These factors include poverty, lack of educational opportunities, lack of access to health care, homophobia , stigma, and racial/ethnic or gender discrimination.
Overall, data show
More information:Many factors may increase HIV risk for some gay, bisexual, or other men who have sex with men (MSM). For example,
More information: Many cultural, socioeconomic, and health-related factors may increase HIV risk for some African Americans and Hispanics/Latinos. For example,
More information: Many cultural, socioeconomic, and health-related factors may increase HIV risk for some transgender people. For example,
More information: In 2018, 7% of new HIV diagnoses in the United States and dependent areas were attributed to injection drug use and another 3% to male-to-male sexual contact and injection drug use (men who reported both risk factors). Of the HIV diagnoses attributed to injection drug use, 58% were among men and 42% were among women.
More information: Many factors may increase HIV risk for some people who inject drugs (PWID). For example,
CDC’s HIV in the United States and Dependent Areas
CDC’s Resources on Injection Drug Use and HIV
CDC’s AtlasPlus: A resource allowing users to create tables, maps, and charts with HIV surveillance data
CDC’s HIV Information by Group:
HIV in the United States by Region
Learn about the Centers for Disease Control and Prevention’s HIV prevention campaigns:
HIV Treatment Works: Encouraging people with HIV to get in care, stay in care, and live well
When people get HIV and don’t receive treatment, they will typically progress through three stages of disease. HIV medicine, known as antiretroviral therapy (ART), helps people at all stages of the disease if taken as prescribed. People with HIV should be begin ART as soon as possible after diagnosis. Treatment can slow the disease or keep it from getting worse. People with HIV who take HIV medicine as prescribed and keep an undetectable viral load can stay healthy and will not transmit HIV to their HIV-negative sex partners.
Within 2 to 4 weeks after someone gets HIV, they may have a flu-like illness, which may last for a few weeks. This is the body’s natural response to infection. This stage is called acute HIV infection. When people have acute HIV infection, they have a large amount of virus in their blood and are extremely contagious. But people with acute infection often don’t know they have HIV because they may not feel sick right away or at all. To know whether someone has acute infection, either an antigen/antibody or nucleic acid (NAT) test is necessary. If you think you have been exposed to HIV through sex or drug use and you have flu-like symptoms, visit a health care provider or clinic immediately and ask for a test to diagnose acute infection.
This period is sometimes called asymptomatic HIV infection or chronic HIV infection. During this phase, HIV is still active but the amount of HIV in the body grows very slowly. People may not have any symptoms or get sick during this time. For people who aren’t taking HIV medicine (ART), this period can last a decade (10 years) or longer, but some may progress through this phase faster. People who are taking HIV medicine as prescribed may be in this stage for several decades. It’s important to remember that you can still transmit HIV to others during this phase unless you are taking HIV medicine and keep an undetectable viral load. If you take HIV medicine as prescribed and keep an undetectable viral load, you will stay healthy and will not transmit HIV to your HIV-negative sex partners. At the end of this phase, if you are not taking your HIV medicine as prescribed, your viral load can increase while your CD4 cell count decreases. As this happens, you may begin to have symptoms as the virus levels increase in your body, and you move into Stage 3.
More Information CD4 cells cause the body’s immune system to start working to fight off infections. HIV attacks the body’s CD4 cells so that it’s harder for the immune system to fight off viruses or infections.
AIDS is the most severe phase of HIV infection. If you have not been effectively treating you HIV with HIV medicines, you will most likely reach Stage 3, called AIDS. People with AIDS have badly damaged immune systems and get an increasing number of severe HIV-related illnesses, called opportunistic illnesses.
More information: Opportunistic illnesses are infections and infection-related cancers that are more common or more severe in people with HIV because their immune systems are damaged. Examples include Kaposi's sarcoma, lymphoma, tuberculosis, and pneumonia.
Without treatment, people with AIDS typically survive about 3 years. Common symptoms of AIDS include chills, fever, sweats, swollen lymph glands, weakness, and weight loss. People receive an AIDS diagnosis when their CD4 cell count drops below 200 cells in a cubic millimeter of blood (200/mm3) or if they develop certain opportunistic illnesses. People with AIDS can have a high viral load and a high chance of transmitting HIV.
CDC’s Living with HIV Basics
Revised Surveillance Case Definitions for HIV Infection---United States, 2014
Learn about the Centers for Disease Control and Prevention’s HIV prevention campaigns:
HIV Treatment Works: Encouraging people with HIV to get in care, stay in care, and live well
What is HIV superinfection? HIV superinfection is when a person with HIV also gets another type, or strain, of the HIV virus. The new strain of HIV can replace the original strain or remain along with the original strain. This usually happens when a person first gets HIV, or soon after they get a new strain.
CDC’s Male Condom Effectiveness Fact Sheet