Every time a person with HIV who is not virally suppressed has sex with an HIV-negative person,there is a chance the HIV-negative partner will get HIV. Some sex acts (such as, kissing, touching, and oral sex) have extremely low to no HIV risk. You have a much higher risk for getting or transmitting HIV through vaginal and anal sex.
Estimate the HIV Risk shows risks when one partner has HIV and the other partner doesn’t. It gives you information for a single sex act at a time. You can change the settings on the tool to get information about a variety of sex acts, to see how one type of sex act is riskier than another.
Choosing to use protective factors (such as condoms, pre-exposure prophylaxis or PrEP , and antiretroviral therapy, or ART) can lower or eliminate the HIV risk for each sex act. This tool provides information on how much each protective factor reduces HIV risk.
Other risk factors (such as having an acute HIV infection or having another STD) can raise the HIV risk for each sex act. This tool also provides information on how much each risk factor increases HIV risk.
Estimate the HIV Risk can give you different kinds of HIV risk information. It can show you:
About the Numbers
If you click on “Show numbers,” you will see the number of times HIV could be transmitted for every 10,000 sex acts. The numbers may seem small, but they show the risk for one sex act. Your risk for getting or transmitting HIV increases every time you have sex with a discordant partner (a partner with a different HIV status).
Sexual activities
Estimate the HIV Risk displays the number 138 for the risk of getting HIV from receptive anal sex. This represents that the risk for getting HIV from receptive anal sex (without condoms, PrEP, or ART) is about 138 per 10,000 sex acts. So, on average for an HIV-negative receptive partner, there is about a 1 in 72 chance of getting HIV for every act of receptive anal sex with an HIV-positive insertive partner. In the anal sex message of the HIV Risk Reduction Tool, the risk is displayed as 1 in 72.
This table outlines how the risk numbers for the other activities in Estimate the HIV Risk are displayed with the messages of the HIV Risk Reduction Tool.
Activity |
Risk Displayed in Know the HIV Risk |
Risk Displayed in the HIV Risk Reduction Tool Messages |
Receptive Anal Sex |
138 |
1 in 72 |
Insertive Anal Sex |
11 |
1 in 909 |
Receptive Vaginal Sex |
8 |
1 in 1250 |
Insertive Vaginal Sex |
4 |
1 in 2500 |
Patel, P., Borkowf, C. B., Brooks, J. T., Lasry, A., Lansky, A., & Mermin, J. (2014). Estimating per-act HIV transmission risk: a systematic review. AIDS, 28(10), 1509-1519. doi: 10.1097/QAD.0000000000000298
PrEP
Protective Factor: Optimal or Consistent PrEP for the HIV negative partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Reduction Estimate |
Estimated Risk of Activity with Protective Factor |
Activity with Protective Factor as Displayed in Estimate the HIV Risk |
Receptive Anal Sex |
138 |
∼99% |
1.38 |
1 |
Insertive Anal Sex |
11 |
∼99% |
.11 |
<.5 |
Receptive Vaginal Sex |
8 |
∼99% |
.08 |
<.5 |
Insertive Vaginal Sex |
4 |
∼99% |
.04 |
<.5 |
Male Condoms
Protective Factor: Male Condoms for the insertive partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Reduction Estimate |
Estimated Risk of Activity with Protective Factor |
Activity with Protective Factor as Displayed in Estimate the HIV Risk |
Receptive Anal Sex |
138 |
72% |
38.64 |
39 |
Insertive Anal Sex |
11 |
63% |
4.07 |
4 |
Receptive Vaginal Sex |
8 |
80% |
1.60 |
2 |
Insertive Vaginal Sex |
4 |
80% |
.80 |
1 |
ART+UVL
Protective Factor: ART+UVL for the HIV-positive partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Reduction Estimate |
Estimated Risk of Activity with Protective Factor |
Activity with Protective Factor as Displayed in Estimate HIV Risk |
Receptive Anal Sex |
138 |
100% |
0 |
0 |
Insertive Anal Sex |
11 |
100% |
0 |
0 |
Receptive Vaginal Sex |
8 |
100% |
0 |
0 |
Insertive Vaginal Sex |
4 |
100% |
0 |
0 |
* If the partner with HIV gets and keeps an undetectable viral load, they will not transmit HIV through sex.
Risk Factors
The risk factors in Estimate the HIV Risk are either partner having another STD, and acute infection. The risk factors are assigned numerical values that express the increase in risk for HIV transmission with the risk factor.
Choosing risk factors in Estimate the HIV Risk will illustrate how much the factor increases the risk of HIV transmission for each act. For example, for receptive anal sex with Acute HIV Infection, Estimate the HIV Risk will display that the HIV risk increases by 7.25, which increases the risk of transmission from 138 per 10,000 exposures to 1001 per 10,000 exposures.
Estimate the HIV Risk displays the increase in estimated risk as the area of the triangle shaded red.
Additional details about these tables can be found on the CDC’s HIV Risk and Prevention Estimates webpage.
Acute HIV Infection
Risk Factor: Acute HIV Infection for the HIV-positive partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Estimate |
Estimate Risk of Activity with Risk Factor |
Activity with Risk Factor as Displayed in Estimate the HIV Risk |
Receptive Anal Sex |
138 |
7.25 |
1000.50 |
1001 |
Insertive Anal Sex |
11 |
7.25 |
79.75 |
80 |
Receptive Vaginal Sex |
8 |
7.25 |
58 |
58 |
Insertive Vaginal Sex |
4 |
7.25 |
29 |
29 |
STDs
Risk Factor: STD infection for the HIV-negative partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Estimate |
Estimated Risk of Activity with Risk Factor |
Activity with Risk Factor as Displayed in Estimate the HIV Risk |
Receptive Anal Sex |
138 |
2.65 |
365.70 |
366 |
Insertive Anal Sex |
11 |
2.65 |
29.15 |
29 |
Receptive Vaginal Sex |
8 |
2.65 |
21.20 |
21 |
Insertive Vaginal Sex |
4 |
2.65 |
10.60 |
11 |
Risk Factor: STD infection for the HIV-positive partner | ||||
Activity |
Risk Displayed in Estimate the HIV Risk |
HIV Risk Estimate |
Estimate Risk of Activity with Risk Factor |
Activity with Risk Factor as Displayed in Estimate the HIV Risk |
Receptive Anal Sex |
138 |
2.58 |
356.04 |
356 |
Insertive Anal Sex |
11 |
2.58 |
28.38 |
28 |
Receptive Vaginal Sex |
8 |
2.58 |
20.64 |
21 |
Insertive Vaginal Sex |
4 |
2.58 |
10.32 |
10 |